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Gynecologic Cancer InterGroup (GCIG) consensus review for mucinous ovarian carcinoma.

Submitted by dcc on Wed, 02/17/2016 - 11:56
TitleGynecologic Cancer InterGroup (GCIG) consensus review for mucinous ovarian carcinoma.
Publication TypeJournal Article
Year of Publication2014
AuthorsLedermann, JA, Luvero, D, Shafer, A, O'Connor, D, Mangili, G, Friedlander, MLeonard, Pfisterer, J, Mirza, MR, Kim, J-W, Alexandre, J, Oza, AM, Brown, J
JournalInt J Gynecol Cancer
Volume24
Issue9 Suppl 3
PaginationS14-9
Date Published11/2014
ISSN1525-1438
KeywordsAdenocarcinoma, Mucinous, Combined Modality Therapy, Consensus, Female, Humans, Medical Oncology, Ovarian Neoplasms, Practice Guidelines as Topic, Societies, Medical
Abstract

Mucinous carcinomas of the ovary can be primary or metastatic in origin. Improvements in the pathological diagnosis have increased the ability to distinguish between primary and metastatic ovarian cancers and shown that primary mucinous carcinomas are a rare subtype of ovarian cancer. Most tumors are diagnosed at an early stage, and the prognosis after surgery is good. Advanced or recurrent mucinous carcinoma of the ovary responds poorly to current cytotoxic treatments, and the prognosis is poor. Here, we review the guidelines for surgery and the results of treatment of advanced and recurrent disease. Chemotherapy with platinum and paclitaxel is currently used to treat advanced disease, but the effect of these drugs is modest, and new treatments are needed.
DOI10.1097/IGC.0000000000000296
Alternate JournalInt. J. Gynecol. Cancer
PubMed ID25341574
Grant ListP30 CA016672 / CA / NCI NIH HHS / United States