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Gynecologic Cancer InterGroup (GCIG) consensus review for ovarian and primary peritoneal low-grade serous carcinomas.

Submitted by dcc on Wed, 02/17/2016 - 11:54
TitleGynecologic Cancer InterGroup (GCIG) consensus review for ovarian and primary peritoneal low-grade serous carcinomas.
Publication TypeJournal Article
Year of Publication2014
AuthorsGourley, C, Farley, J, Provencher, DM, Pignata, S, Mileshkin, LR, Harter, P, Maenpaa, JU, Kim, J-W, Pujade-Lauraine, E, Glasspool, RM, Ray-Coquard, I, Gershenson, D
JournalInt J Gynecol Cancer
Volume24
Issue9 Suppl 3
PaginationS9-13
Date Published11/2014
ISSN1525-1438
KeywordsCombined Modality Therapy, Consensus, Cystadenocarcinoma, Serous, Female, Humans, Medical Oncology, Neoplasm Grading, Ovarian Neoplasms, Peritoneal Neoplasms, Practice Guidelines as Topic, Societies, Medical
Abstract

Low-grade serous ovarian cancer is a recently described histological subtype of ovarian cancer that is clinically and molecularly distinct from the 4 other main histological subtypes (high-grade serous, clear cell, endometrioid, and mucinous). In particular, it differs from high-grade serous ovarian cancer in that it presents at a much younger age, is more indolent, and is relatively chemoresistant. Very few clinical trials have been performed exclusively in this tumor type; and as such, specific data guiding optimal management are limited.
DOI10.1097/IGC.0000000000000257
Alternate JournalInt. J. Gynecol. Cancer
PubMed ID25341587
Grant ListP30 CA016672 / CA / NCI NIH HHS / United States
SCD/11 / / Chief Scientist Office / United Kingdom