Clinical Trials

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Disease Site Trial Trial Description Trial Status Sort descending Lead Cooperative Group
Cervical Empower Cervical 1/ ENGOT-Cx9/ GEICO 72-C/ GOG-3016

An Open Label, Randomized, Phase 3 Clinical Trial of REGN2810 Versus Therapy of Investigator’s Choice Chemotherapy in Recurrent or Metastatic Platinum-Refractory Cervical Carcinoma

Completed GEICO
Cervical MITO CERV 2

Study of Adding Cetuximab to Chemotherapy for the Treatment of Advanced and/or Recurrent Cervical Cancer (MITO CERV 2)

Completed MITO
Cervical/Endometrial GOG233/ACRIN6671

Fludeoxyglucose F 18 PET Scan, CT Scan, and Ferumoxtran-10 MRI Scan Before Chemotherapy and Radiation Therapy in Finding Lymph Node Metastasis in Patients With Locally Advanced Cervical Cancer or High-Risk Endometrial Cancer 

Closed to Recruitment GOG-F
Endometrial MK-2870-005-ENGOT-en23

A Phase 3, Randomized, Active-controlled, Open-label, Multicenter Study to Compare the Efficacy and Safety of MK-2870 Monotherapy Versus Treatment of Physician’s Choice in Participants With Endometrial Cancer Who Have Received Prior Platinum-based Chemotherapy and Immunotherapy

Pending MITO
Endometrial SAVE

Short Course Adjuvant Vaginal Cuff Brachytherapy (VCB) in Early Endometrial Cancer Compared to Standard of Care (SAVE)

Recruiting COGI-WCRN
Endometrial AEC

Cytoreductive Surgery in Advanced Endometrial Cancer. Multicenter Retrospective Study

Recruiting MITO
Endometrial E.C.Co.

Endometrial Cancer Conservative treatment. A multicentre archive

Recruiting MITO
Endometrial Rainbo-MMRd-GREEN

Rainbo: Refining adjuvant treatment IN endometrial cancer based on molecular features, transportec platform trials - MMRd - Green

Recruiting DGOG
Endometrial C93GOG-3064 ENGOT-en15

A Phase 3 Randomized, Open-label, Active-comparator Controlled Clinical Study of Pembrolizumab versus Platinum Doublet Chemotherapy in Participants With Mismatch Repair Deficient (dMMR) Advanced or Recurrent Endometrial Carcinoma in the First-line Setting

Recruiting MITO
Endometrial AGO-OP.6/ECLAT

Endometrial Cancer Lymphadenectomy Trial (ECLAT)

Recruiting AGO
Endometrial KGOG 2029/ SELYE

Randomized comparison between sentinel lymph node mapping using indocyanine green plus a fluorescent camera versus lymph node dissection in clinical stage I-II endometrial cancer: a Korean Gynecologic Oncology Group trial

Recruiting KGOG
Endometrial ENGOT-EN20/GOG-3083/XPORT-EC-042

A Phase 3, Randomized, Placebo-Controlled, double-blind, multicenter trial of selinexor in maintenance therapy after systemic therapy for patients with p53 wild-type, advanced or recurrent endometrial carcinoma

Recruiting BGOG
Endometrial DOMENICA

Randomized phase III trial in MMR deficient endometrial cancer patients comparing chemotherapy alone versus Dostarlimab in first line advanced/metastatic setting

Recruiting GINECO
Endometrial CCTG EN.10: RAINBO BLUE AND TAPER

A Phase II Study of Tailored Adjuvant Therapy in POLE-mutated and p53-wildtype/NSMP Early Stage Endometrial Cancer (RAINBO BLUE & TAPER)

Recruiting CCTG
Endometrial PORTEC-3

Randomized Phase III Trial Comparing Concurrent Chemoradiation and Adjuvant Chemotherapy with Pelvic Radiation Alone in High Risk and Advanced Stage Endometrial Carcinoma

Closed to Recruitment DGOG
Endometrial GOG 0258

Carboplatin and Paclitaxel with or Without Cisplatin and Radiation Therapy in treating Patients with Stage I, Stage II and Sage III or Stage IVA Endometrial Cancer

Closed to Recruitment GOG-F
Endometrial PORTEC-4a

Randomised Phase III Trial of molecular profile-based versus standard recommendations for adjuvant radiotherapy for women with early stage endometrial cancer

Closed to Recruitment DGOG
Endometrial ENGOT-EN2 / DGCG

A phase II Trial of postoperative chemotherapy or no further treatment for patients with node-negative stage I-II intermediate or high risk endometrial cancer.

Closed to Recruitment NSGO-CTU
Endometrial ENGOT-EN3 / NSGO - PALEO

Trial of Letrozole +/- Palbociclib in Metastatic Endometrial Cancer

Closed to Recruitment NSGO-CTU
Endometrial ENGOT-EN5/GOG- 3055/SIENDO

A randomized, double-blind, phase 3 trial of maintenance with selixexor/placebo after combination chemotherapy for patients with advanced or recurrent endometrial cancer. 

Closed to Recruitment BGOG