Clinical Trials

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Disease Site Trial Sort ascending Trial Description Trial Status Lead Cooperative Group
Cervical A18-00/ENGOT-CX11

A Randomized, Phase 3, Double-Blind Study of Chemoradiotherapy With or Without Pembrolizumab for the Treatment of High-risk, Locally Advanced Cervical Cancer

Recruiting MITO
Cervical 55994

Randomized phase III study of neoadjuvant chemotherapy followed by surgery vs. concomitant radiotherapy and chemotherapy in FIGO Ib2, IIa > 4 cm or IIb cervical cancer

Closed to Recruitment EORTC-GCG
Cervical/Endometrial GOG233/ACRIN6671

Fludeoxyglucose F 18 PET Scan, CT Scan, and Ferumoxtran-10 MRI Scan Before Chemotherapy and Radiation Therapy in Finding Lymph Node Metastasis in Patients With Locally Advanced Cervical Cancer or High-Risk Endometrial Cancer 

Closed to Recruitment GOG-F
Endometrial TOTEM

Trial between Two Follow up Regimens with Different Intensity in Endometrial Cancer Treated Patients

Completed MaNGO
Endometrial STATEC

A randomised trial of non-Selective versus selective adjuvant Therapy in high risk Apparent sTage 1 Endometrial Cancer

Completed NCRI
Endometrial SAVE

Short Course Adjuvant Vaginal Cuff Brachytherapy (VCB) in Early Endometrial Cancer Compared to Standard of Care (SAVE)

Recruiting COGI-WCRN
Endometrial Rainbo-MMRd-GREEN

Rainbo: Refining adjuvant treatment IN endometrial cancer based on molecular features, transportec platform trials - MMRd - Green

Recruiting DGOG
Endometrial PORTEC-4a

Randomised Phase III Trial of molecular profile-based versus standard recommendations for adjuvant radiotherapy for women with early stage endometrial cancer

Closed to Recruitment DGOG
Endometrial PORTEC-3

Randomized Phase III Trial Comparing Concurrent Chemoradiation and Adjuvant Chemotherapy with Pelvic Radiation Alone in High Risk and Advanced Stage Endometrial Carcinoma

Closed to Recruitment DGOG
Endometrial MK-2870-005-ENGOT-en23

A Phase 3, Randomized, Active-controlled, Open-label, Multicenter Study to Compare the Efficacy and Safety of MK-2870 Monotherapy Versus Treatment of Physician’s Choice in Participants With Endometrial Cancer Who Have Received Prior Platinum-based Chemotherapy and Immunotherapy

Pending MITO
Endometrial KGOG 2029/ SELYE

Randomized comparison between sentinel lymph node mapping using indocyanine green plus a fluorescent camera versus lymph node dissection in clinical stage I-II endometrial cancer: a Korean Gynecologic Oncology Group trial

Recruiting KGOG
Endometrial KGOG 2015

Prospective, Observational Study of Low-risk Criteria for Node Metastasis in Endometrial Cancer 

Completed KGOG
Endometrial GOG 0258

Carboplatin and Paclitaxel with or Without Cisplatin and Radiation Therapy in treating Patients with Stage I, Stage II and Sage III or Stage IVA Endometrial Cancer

Closed to Recruitment GOG-F
Endometrial ENGOT-EN5/GOG- 3055/SIENDO

A randomized, double-blind, phase 3 trial of maintenance with selixexor/placebo after combination chemotherapy for patients with advanced or recurrent endometrial cancer. 

Closed to Recruitment BGOG
Endometrial ENGOT-EN3 / NSGO - PALEO

Trial of Letrozole +/- Palbociclib in Metastatic Endometrial Cancer

Closed to Recruitment NSGO-CTU
Endometrial ENGOT-EN20/GOG-3083/XPORT-EC-042

A Phase 3, Randomized, Placebo-Controlled, double-blind, multicenter trial of selinexor in maintenance therapy after systemic therapy for patients with p53 wild-type, advanced or recurrent endometrial carcinoma

Recruiting BGOG
Endometrial ENGOT-EN2 / DGCG

A phase II Trial of postoperative chemotherapy or no further treatment for patients with node-negative stage I-II intermediate or high risk endometrial cancer.

Closed to Recruitment NSGO-CTU
Endometrial ENGOT-EN11/GOG-3053/KEYNOTE-B21

A Phase 3, Randomized, Double-Blind Study of Pembrolizumab versus placebo in combination with adjuvant chemotherapy with or without radiotherapy for the treatment of newly diagnosed High-Risk Endometrial Cancer after surgery with curative Intent

Closed to Recruitment BGOG
Endometrial E.C.Co.

Endometrial Cancer Conservative treatment. A multicentre archive

Recruiting MITO
Endometrial DOMENICA

Randomized phase III trial in MMR deficient endometrial cancer patients comparing chemotherapy alone versus Dostarlimab in first line advanced/metastatic setting

Recruiting GINECO