Clinical Trials

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Disease Site Trial Sort ascending Trial Description Trial Status Lead Cooperative Group
Endometrial CCTG EN.10: RAINBO BLUE AND TAPER

A Phase II Study of Tailored Adjuvant Therapy in POLE-mutated and p53-wildtype/NSMP Early Stage Endometrial Cancer (RAINBO BLUE & TAPER)

Recruiting CCTG
Endometrial C93GOG-3064 ENGOT-en15

A Phase 3 Randomized, Open-label, Active-comparator Controlled Clinical Study of Pembrolizumab versus Platinum Doublet Chemotherapy in Participants With Mismatch Repair Deficient (dMMR) Advanced or Recurrent Endometrial Carcinoma in the First-line Setting

Recruiting MITO
Endometrial AtTEnd/ENGOT-EN7

Phase III double-blind randomized placebo controlled trial of atezolizumab in combination with paclitaxel and carboplatin in women with advanced/recurrent endometrial cancer

Closed to Recruitment MaNGO
Endometrial AGO-OP.6/ECLAT

Endometrial Cancer Lymphadenectomy Trial (ECLAT)

Recruiting AGO
Endometrial AEC

Cytoreductive Surgery in Advanced Endometrial Cancer. Multicenter Retrospective Study

Recruiting MITO
Fallopian Tube & Ovarian VIP

Phase II Study of Intravenous Vinorelbine in Patients With Relapsed Platinum Resistant or Refractory C5 High Grade Serous, Endometrioid, or Undifferentiated Primary Peritoneum, Fallopian Tube or Ovarian Cancer

Recruiting GCGS
Gestational Trophoblastic Neoplasia GOG 0275

Dactinomycin or Methotrexate in Treating Patients with Low Risk Gestational Trophoblastic Neoplasia

Recruiting GOG-F
Ovarian TEDOVA

OSE2101 Alone or in Combination With Pembrolizumab vs BSC in Patient With Platinum-sensitive Recurrent OC

Recruiting GINECO
Ovarian Tarceva Trial EORTC 55041

A randomised, multicentre, phase III study of Erlotinib versus observation in patients with no evidence of disease progression after first line, platinum-based chemotherapy for high-risk Stage I and Stage II-IV ovarian epithelial, primary peritoneal, or fallopian tube cancer.

Completed EORTC-GCG
Ovarian SUNNY/SGOG OV4B

A Study of Upfront Surgery Versus Neoadjuvant Chemotherapy Followed by Interval Debulking Surgery for Patients With Stage IIIC and IV Ovarian Cancer(SUNNY)

Recruiting SGOG
Ovarian SALVOVAR

A pragmatic randomized phase III trial to assess the utility of adjusting chemotherapy dose & dosing schedule with the SALVage weekly dose-dense regimen in patients with poor prognostic OVARian cancers based on the tumor primary chemosensitivity and incomplete debulking surgery

Pending GINECO
Ovarian PMHC – NEO / OZM-058

A Phase II, Open-Label, Randomized, Multi-Centre Study of Neoadjuvant Olaparib in Patients with Platinum Sensitive Recurrent High Grade Serous Ovarian/Primary Peritoneal or Fallopian tube Cancer

Closed to Recruitment PMHC
Ovarian PMHC – eVolve-1 / OZM-060

A Proof of Concept, Multi-centre, Clinical Trial of the Combination Cediranib-Olaparib at the Time of Disease Progression on PARP Inhibitor in Ovarian Cancer 

Closed to Recruitment PMHC
Ovarian PAOLA-1

Platine, Avastin and Olaparib in 1st line Ovarian Cancer

Completed GINECO
Ovarian NSGO-CTU/HERO

Characterization of High-Grade Ovarian Cancer Patients in Terms of Homologous Recombination Phenotype – A Prospective Observational Study

Recruiting NSGO-CTU
Ovarian NIRVANA-1

A Randomized Study of Paclitaxel – Carboplatin followed by maintenance Niraparib compared to Paclitaxel – Carboplatin – Bevacizumab followed by maintenance Niraparib + Bevacizumab in Patients With Advanced Ovarian Cancer, Following a Front-Line Complete Cytoreductive Surgery

Recruiting GINECO
Ovarian MOCCA

A Multicentre Phase II Randomised Trial of Durvalumab (MEDI4736) Versus Physician's Choice Chemotherapy in Recurrent Ovarian Clear Cell Adenocarcinomas

Completed GCGS
Ovarian MITO7

First line weekly carboplatin and paclitaxel versus every 3 weeks carboplatin/paclitaxel in patients with ovarian cancer: phase III multicentre trial 

Completed MITO
Ovarian MITO23

Randomized phase III  trial on  Trabectedin (ET 743) vs clinician’s choice chemotherapy   in recurrent ovarian, primary peritoneal or fallopian tube cancers of BRCA mutated or  BRCAness phenotype patients 

Completed MITO
Ovarian MITO12

Pathway to diagnosis of ovarian cancer: an observational retrospective multicentred study 

Completed MITO